He has worked with numerous artists, including Tove Lo, Theo Hutchcraft, Ryan Tedder, Hailee Steinfeld, Calvin Harris, Anitta, Usher, David Guetta, Sebastian Ingrosso, Liam Payne, Tini and Stray Kids.
He has performed at numerous music festivals, including Coachella, Electric Daisy Carnival, Creamfields, and Tomorrowland. In 2012, MTV named Alesso one of the “EDM Rookies to Watch”.
He was ranked 13th on DJ Magazine’s 2015 list of the top 100 DJs and number 20th in year 2016 on DJ Magazine among the list of Top 100 DJs in the world. His debut full-length album Forever was released on 22 May 2015 by Def Jam Recordings.
Alesso finished off his year with a New Year’s Eve performance at Miami’s Fontainebleau Resort. He co-headlined the show with Colombian reggaeton star J Balvin where the two played at the venue’s poolside.
On January 29, 2019 it was announced that Alesso will perform at the Indy 500 Snake Pit on May 26, 2019, along with Skrillex, Illenium, and Chris Lake. Previous performers have included: Axwell Λ Ingrosso, deadmau5, Diplo, GRiZ, Zedd, Marshmello, Martin Garrix, Steve Aoki, Kaskade, Hardwell, Dillon Francis, and Zeds Dead.
On February 22, 2019 he performed at the concert Venezuela Live Aid alongside influencers Lele Pons and Juanpa Zurita to help raise funds to fight Venezuelan humanitarian crisis.
In November 2020, Alesso performed at Road to Ultra Taiwan, one of the few major music events still taking place in 2020 despite the COVID-19 pandemic.